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Examining the principles and methods of research on the evaluation of factors affecting the outcome of illness, this book emphasizes diagnostic and therapeutic interventions--the factors most readily modified by health care providers. The author discusses various ways of structuring observations on patient groups, and appraises the nature and strength of inferences drawn from those observations. He also demonstrates how the results of this type of research--clinical epidemiologic research--can be incorporated into the decision-making process utilized in clinical medicine.
This book contains a concise account of topics such as the assessment of the use of diagnostics and screening tests and their role in improving the outcome of illness, the evaluation of therapeutic efficacy through experimental and nonexperimental studies, and a particularly useful chapter on assessment of therapeutic safety. It is an essential reference and guide to the quantitative assessment of the consequences of illness for clinicians in training or in practice.The new edition of Clinical Epidemiology greatly expands the chapter on randomized control trials, and includes a whole new chapter on meta-analysis, authored by Peter Cummings. Meta-analysis, the statistical synthesis of data from comparable studies, was unheard of 30 years ago, but with the advent of increased computer technology, the method has been steadily growing in importance in the epidemiology community.
- Sales Rank: #1366075 in Books
- Published on: 2006-06-01
- Original language: English
- Number of items: 1
- Dimensions: 6.30" h x .90" w x 9.30" l, .98 pounds
- Binding: Hardcover
- 192 pages
Review
From reviews of the First Edition:
"Although this book is short, it is rich in substance. Weiss describes basic epidemiologic applications of clinical decision making in clear, concise language, with many references to real patient situations and to published investigations....Clinicians in training or in practice would find this book helpful as a reference and guide to the quantitative assessment of the consequences of illness."--The New England Journal of Medicine
"A worthwhile addition to the departmental library of any unit where clinical research is carried out or contemplated."--Annals of Internal Medicine
"The material was originally designed as a public health course in clinical epidemiology. As such the book is extremely useful."--International Journal of Epidemiology
"A concise account of topics such as the assessment of the use of diagnostics and screening tests and their role in improving the outcome of illness, the evaluation of therapeutic efficacy through experimental and nonexperimental studies, and a particularly useful chapter on assessment of therapeutic safety....A real strength of the book comes at the end of each chapter where a few well-chosen questions derived from published studies of a wide range of clinical topics, accompanied by simple unambiguous answers, have been placed to 'encourage the active participation' of the reader."--Lancet
"Well-researched and contains much information useful to the beginning clinical epidemiologist....Clinically oriented and reflects a refreshingly practical bent, as well as humane concern for the subjects of our research efforts....This book is to be recommended. It would be a useful addition to the libraries of medical schools, and the personal libraries of those persons who participate in clinical research."--The Epidemiology Monitor
"A joy to read...A pragmatic and real-world guide for those who wish to make the best decisions for their patients and for those planning studies to answer clinical questions."--Journal of General Internal Medicine
About the Author
Noel S. Weiss is a Professor in the Department of Epidemiology, University of Washington, Seattle.
Most helpful customer reviews
3 of 4 people found the following review helpful.
Excellent book
By M. Sorensen
This book was a reference for the course "Clinical Epidemiology" taught by Noel Weiss. I originally borrowed this from the library, but after completing the course, I have realized this is a book I want to have onhand forever. Clear, concise with excellent examples. The chapters excellently describe the subtle issues with RCTs, case control, cohort studies and those designed to measure safety.
0 of 0 people found the following review helpful.
Examining the principles and methods of research on the evaluation ...
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Examining the principles and methods of research on the evaluation of factors affecting the outcome of illness, this book emphasizes diagnostic and therapeutic interventions--the factors most readily modified by health care providers. The author discusses various ways of structuring observations on patient groups, and appraises the nature and strength of inferences drawn from those observations. He also demonstrates how the results of this type of research--clinical epidemiologic research--can be incorporated into the decision-making process utilized in
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